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there is not enough scientific data to prove their safety

22 Interleukin-6, vascular endothelial growth factor, insulin-like growth factor-1 and Annexin V assay kit were from Life Technologies (Carlsbad, CA, USA)

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Immunohistochemistry NF-B examination Immunohistochemistry (IHC) was performed using the avidin-biotin complex (ABC) method as previously described by Hsu et al

This creates an interesting paradox: the concentrations listed on product labels far exceed what cells actually need to respond

Notably, the PROTACs that have advanced into clinical studies are, in most cases, still based on this small-molecule design paradigm, rather than on macromolecular or biomacromolecular carrier systems