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Glucagon receptor activation drives hepatic glucose output and, critically, increases energy expenditure through thermogenesis

[3] Falutz J, Mamputu JC, Potvin D, Moyle G, Soulban G, Loughrey H, Marsolais C, Turner R, Grinspoon S

Metabolic reprogramming can regulate the expression of metabolism-related genes (e.g., thioredoxin reductase 1, TXNRD1), which exerts redox/antioxidant regulatory functions and participates in COPD-related metabolic disturbance processes by regulating redox balance (115)