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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Kanie T, Onoyama I, Matsumoto A, Yamada M, Nakatsumi H, Tateishi Y, et al

Stage 1: Composition of Matter Patent (Years 0-20 from filing) The COM patent covers the active pharmaceutical ingredient itself, its salts, and often its major polymorphs

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Store lyophilized AOD 9604 refrigerated between 2C and 8C (36F to 46F), protected from direct light and moisture

Huperzine A (from Huperzia serrata ), an acetylcholinesterase (AChE) inhibitor that enhances memory by increasing acetylcholine (ACh) level shown to improve memory and inhibit glutamate-induced excitotoxicity (Qian and Ke, 2014

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