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The MOTS-c peptide , encoded in mitochondrial DNA, has therefore been investigated as a potential tool for extending healthspan and delaying age-related decline

Inhibition of pyruvate kinase M2 markedly reduces chemoresistance of advanced bladder cancer to cisplatin

Yang Y, Churchward-Venne TA, Burd NA, Breen L, Tarnopolsky MA, Phillips SM

When nematodes were pretreated with MT or 6a for 48 h at L1, the GFP expression loss was remarkably restored in CEP and ADE neurons (Figure 6B)

For the BPAM344/glutamate sample, proteins were pre-incubated with 500 M BPAM344 for 30 min on ice, followed by the addition of 1 mM glutamate to the sample

Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus