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Low doses of GHB can cause nausea, while high doses can lead to: Unconsciousness Seizures Slowed heart rate Considerably slowed breathing Lower body temperature Vomiting Nausea Coma Death Alcohol worsens all of these symptoms and it can lead to an overdose

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A serious systemic disturbance called metabolic acidosis can occur in CKD when acidic compounds, especially nitrogen-containing waste from dietary protein metabolism, accumulate in the blood

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354 2733 Liang BC and Hays L 1996 Mitochondrial DNA copy number changes in human gliomas

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