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TMAO is a metabolite produced by the intestinal flora, and it has gained significant attention in recent years due to its potential role in cardiovascular disease (17)

The TMAO was shown to promote the upregulation of the scavenger receptors CD36 and SR-A1 11 as well as induce inflammation 12 via the MAPK/JNP pathway, which regulates the synthesis of pro-inflammatory cytokines tumor necrosis factor alpha (TNF-), interleukin 6 (IL-6) and intercellular adhesion molecule 1 (ICAM-1)

The Polar H10 was specifically chosen for its ability to provide consistent real-time heart rate data, a key indicator of exercise intensity and endurance capacity

A distinctive symptom of patients with long COVID is post-exertional malaise, which is associated with a worsening of fatigue- and pain-related symptoms after acute mental or physical exercise, but its underlying pathophysiology is unclear

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therefore, transgene expression is dependent on precise integration into the targeted 3 site of ALB to be driven by the endogenous ALB promoter [13]