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Understanding this helps me optimize treatment protocols

Together with the other reports measuring less FDG uptake or a decline in intratumoral lactate levels as summarized in Table 2, this implies that a KD is able to influence tumor cell metabolism by lowering insulin levels and increasing ketone body concentrations

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Antibiotic therapy and treatment failure in patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease

Blaser H, Dostert C, Mak TW, Brenner D

This cascade activates caspase-8 and downstream caspase-3 (Takahashi et al., 1999), leading to DNA fragmentation and keratinocyte apoptosis (Simon et al., 2006)