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Regardless of timing, the following general measures may help manage side effects: Eat smaller, more frequent meals rather than large portions Avoid high-fat or spicy foods around the time of injection Stay well hydrated to reduce nausea and support kidney function When to seek urgent medical attention: Contact your GP, trial team, or NHS 111 promptly if you experience severe or persistent abdominal pain (particularly if it radiates to the back), vomiting that prevents you from keeping fluids down, signs of jaundice (yellowing of the skin or eyes), fever, or significantly reduced urine output

As a water-soluble vitamin, B12 plays a vital role in the body's metabolism and neurological functions

IBM Corp., Armonk, NY, USA)

doi: 10.1038/nm1613 145 ZhangLHeJWangJLiuJChenZDengBet al

Maintenance treatment of hyperammonemia in patients with carbamylphosphate synthetase deficiency, ornithine carbamyl transferase deficiency

Abstract The involvement of cellular senescence in the initiation and propagation of diseases is clearly characterized, making the elimination of senescent cells essential to treat age-related diseases