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J Craniofac Surg 20(1):21-3, 2009

GrossMIDemoSDDennisonJBChenLChernov-RoganTGoyalBet al

By acting as the essential spark plug for these enzymatic reactions, Alpha Lipoic Acid improves mitochondrial structure and function and elevates cofactors of defective mitochondrial enzymes

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If taken late at night, a minority of users feel it could disrupt sleep or make it harder to wind down (this isnt universally reported, but caution is advised)

The PGK1 gene is located on the X chromosome, within the confirmed susceptibility region for PD known as PARK12, suggesting that PGK1 may be directly involved in the disease [68]