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Description

& Shafer, J

Another central feature is the loss of protein balance, especially involving TDP-43, a protein that is abnormally located in the cytoplasm instead of the nucleus in about 97% of ALS cases

Chronic inflammation, often driven by oxidative stress, is a common feature of autoimmune diseases

Thus, the characterization of functional therapeutic agents that stimulate the differentiation of OPCs into mature OLs is of interest for the treatment of neurodevelopmental disorders