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When HCY and B12 levels are high, the enzyme MS converts HCY to methionine, which is then converted to SAM

BMC Complement Altern Med 2012;12:200

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Determination of serum and colon tissue oxidative stress and inflammatory cytokine levels The levels of inflammatory cytokines (TNF-, IL-1, and IL-6) in colon tissue homogenate supernatants were quantified using commercial enzyme-linked immunosorbent assay (ELISA) kits (TNF-: Cat