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Collectively, these findings indicate that incretin mimetics provide neuroprotection extending beyond metabolic regulation by targeting multiple pathogenic processes in PD, including mitochondrial dysfunction, neuroinflammation from oxidative stress, sirtuin dysregulation, insulin resistance, and S toxicity (Meissner et al., 2024)

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doi:10.3390/ijms20030465 50

Author Contributions Concept and design: Karthikeyan Ramalingam, Ameena M, Meignana Arumugham I Acquisition, analysis, or interpretation of data: Karthikeyan Ramalingam, Ameena M, Rajeshkumar Shanmugam Drafting of the manuscript: Karthikeyan Ramalingam, Ameena M, Meignana Arumugham I, Rajeshkumar Shanmugam Critical review of the manuscript for important intellectual content: Karthikeyan Ramalingam Supervision: Karthikeyan Ramalingam References 1.Coconut phytocompounds inhibits polyol pathway enzymes: implication in prevention of microvascular diabetic complications