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Furthermore, recent in vitro studies investigating the effects of the SARS-CoV-2 spike protein on human peripheral blood mononuclear cells (PBMCs) have shown that the introduction of bioavailable glutathione significantly reduces malondialdehyde (MDA), a primary, destructive biomarker for lipid peroxidation and oxidative stress

Additionally, a reduction of approximately 66% in circulating interferon-gamma levels was reported

Lancet 356 , 233241 (2000)

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[32] It has also been shown to improve type 2 diabetes markers, such as several lipid parameters, as well as lower oxidative stress

Low-dose oxidative stress triggers a conformational change in the Keap1 protein, releasing the transcription factor Nrf2