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The brain substantia nigra in PD has a high level of expression of the VD metabolizing enzyme and 1 hydroxylase, and VD can stimulate the expression of tyrosine hydroxylase, a key enzyme of dopamine synthesis in PD, which affects the production and turnover of dopamine, therefore, the role of VD in the development process of PD has received increasing attention (85, 86)
doi: 10.1016/j.plantsci.2004.07.001 77 HemalathaS.AnburajA.FrancisK
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CJC-1295: A longer-acting GHRH analog (30-minute half-life without DAC, or 6-8 days with DAC) that sustains GH pulse frequency and drives a 1.5-3x increase in IGF-1 levels for up to 9-11 days per dose
doi: 10.1007/s00262-003-0493-5 110 SvaneIMPedersenAEJohansenJSJohnsenHENielsenDKambyCet al
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