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Sustained reduction in serum urate levels using urate-lowering therapy is vital in the long-term management of gout, which aims to dissolve MSU crystals, suppress gout flares and resolve tophi

However, both of these first-generation LAIs had a lower risk of psychiatric hospitalization relative to oral risperidone despite having a higher risk of discontinuation

Aging Cell 6:607618 Le Bourg E (2005) Hormetic protection of Drosophila melanogaster middle-aged male flies from heat stress by mildly stressing them at young age

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Ultrafiltration, precipitation with solvents and liquid chromatography techniques (e.g., ion exchange, gel filtration) have been proposed for purification of peptides, however, their current implicit high costs make them prohibitive for large scale applications

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