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Maturation skews macrophage polarization from M1 to M2 (interleukin-4 [IL-4], interleukin-10 [IL-10], IL-12, Arginase 1 [Arg-1]

[12] A further complication of severe deficiency is the neurological complex known as subacute combined degeneration of spinal cord

For example, Bentamapimod has completed a phase 2 trial of endometriosis, and Tanzisertib has been investigated in multiple clinical trials, including for idiopathic pulmonary fibrosis

While our study confirms that LicoA alleviates cisplatin-induced nephrotoxicity by activating the Nrf2/GPX4 axis and inhibiting ferroptosis, there are several limitations that should be addressed in future investigations

While tests such as CVLT, BNT, and UPSIT offer valuable diagnostic insight, particularly in early or prodromal stages, their limited dynamic range and susceptibility to ceiling or floor effects constrain their utility as response biomarkers