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Nat Chem Biol 4:278286 Winterbourn CC, Hampton MB (2008) Thiol chemistry and specificity in redox signaling

The promotion of cytoprotective mechanisms represents the third crucial research direction, with glucagon-like peptide-1 (GLP-1) receptor agonists garnering particular interest

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46,7375 It is therefore suggested that metformin use may be an agent of iatrogenic potential inducing peripheral neuropathy exacerbation in individuals with T2DM who have depressed Vitamin B12, as a result of elevated fasting methylmalonic acid (MMA) and tHcy levels