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It inhibits hippocampal neurogenesis, reduces BDNF expression, and activates the HPA axis, resulting in sustained cortisol elevation (Hodes et al., 2015

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S1G), findings further supported by elevated serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) (Fig

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4.2 Intravenous administration Intravenous (IV) administration ensures 100% bioavailability of the drug in the bloodstream and allows for the most rapid and highest plasma concentrations

For oral B12 supplementation with a supplement like Cobalequin, 250 micrograms must be given once daily and continued initially for 12 weeks