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19 Following further translocation to the mitochondria, activated phosphorylated JNK initiates a cascade in which JNK binds to the outer mitochondrial membrane scaffold protein Sab, inhibiting electron transport and thereby increasing the generation of ROS and peroxynitrite

J Chromatogr B Analyt Technol Biomed Life Sci 1019:5158 Giustarini D, Colombo G, Garavaglia ML, Astori E, Portinaro NM, Reggiani F, Badalamenti S, Aloisi AM, Santucci A, Rossi R, Milzani A, Dalle-Donne I (2017) Assessment of glutathione/glutathione disulphide ratio and S -glutathionylated proteins in human blood, solid tissues, and cultured cells

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Tanaka, H., et al., E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

doi: 10.1002/hep.26697