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Reconstituted material should be stored only under controlled conditions appropriate for short-term analytical use

Vitamin B 12 can be converted to coenzyme B 12 in tissues, and as such is essential for conversion of methylmalonate to succinate and synthesis of methionine from homocysteine, a reaction which also requires folate

doi:10.1007/s12291-010-0042-x

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Reprod Biomed 13:96100 Boquet M, Selva J, Auroux M (1995) Effects of cooling and equilibration in DMSO, and cryopreservation of mouse oocytes on the rates of in vitro fertilization, development, and chromosomal abnormalities

For example, one review analysis of 12 studies found that research participants who took an ALA supplement lost about 1.5 pounds more during the study periods (which averaged 14 weeks) than those who got placebos