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Lie MRKL, van der Giessen J, Fuhler GM, de Lima A, Peppelenbosch MP, van der Ent C, van der Woude CJ

revealed that VEGF significantly upregulates the transcription factor TOX, which influences the phenotype and function of CTLs

Motta F, Bizzaro N, Giavarina D, Franceschini F, Infantino M, Palterer B, et al

The things that lead to this faulty immune response arent clear, but scientists think they can include many factors

Combining angiopoietin-2 (Ang-2) suppression with VEGF pathway blockage can boost the beneficial effect on immune response [110,111]

Alternatively, separate the modalities entirely by using them at different times of day