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Long-term glycemic control and prevention of diabetes complications in vivo using oleic acid-grafted-chitosan-zinc-insulin complexes incorporated in thermosensitive copolymer

*Correspondence: Fu-Hua Lu, [email protected]

By applying this approach, two aptamers (Apta9 and Apta10), which also showed significant sequence identity, displayed specific binding not only to the soluble recombinant CspZ protein, but also to the native protein expressed at the bacterial surface