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Toxicol in Vitro 21: 12411246 Wong CH, Bozinovski S, Hertzog PJ, Hickey MJ, Crack PJ (2008) Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion

In Encyclopedia Britannica

Your natural GHK-Cu levels decline roughly 60% by age 60

S100 plays a role in dealing with oxidative stress hence this increase is perhaps indicative of increased oxidative stress (Hu and Lin, 2021)

So at the end of the day, a lot of it comes down to what youre comfortable with

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