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Although several preclinical studies and clinical trials aimed at reducing oxidative stress using various anti-oxidant molecules have been performed (Rueda Revilla and Martnez-Cu, 2020), none of them has looked at the level of CBS expression and/or activity

Historically, turmeric has been used to treat stomach and liver ailments, as well as general pain in the body

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Inhibiting oxalate formation curbs inflammation and fibrosis Considering that AGXT overexpression attenuated hepatic inflammation and fibrosis in MASH, we next sought to determine whether the pharmacological targeting of hepatic oxalate overproduction in mice with established MASH is sufficient to suppress proinflammatory and profibrotic responses

Sergey Terushkin, MD, FACS Dr