glutathion aufbau Glutathione (reduced glutathione, GSH) endogenous

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Nevertheless, converting azathioprine to 6-MP requires GST enzymatic activity which certainly expands the library of potential gut bacterial candidates for the metabolism of azathioprine

10.1186/s40478-017-0461-5 248 UmedaT.TomiyamaT.SakamaN.TanakaS.LambertM

The fact that the inhibitor of gamma-glutamylcysteine synthetase did not alter the response of glutathione is of importance, since it demonstrates that the increase of intracellular concentration of glutathione is not required to reduce the cell index

Jabir NR, Rehman MT, AlAjmi MF, Ahmed BA, Tabrez S (2023) Prioritization of bioactive compounds envisaging yohimbine as a multi targeted anticancer agent: insight from molecular docking and molecular dynamics simulation

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