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Based on target prediction, bioinformatics analysis, molecular docking, and CETSA, we identified EGFR as the target of QCT (Fig

Both disorders involve protein clearance dysfunction: AD is associated with amyloid-beta and tau accumulation, while SCA3 is associated with mutant ataxin-3 aggregates that disrupt autophagy by destabilizing Beclin-1 1,82

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prausnitzii) is a commensal anaerobe belonging to the phylum Bacillota and is the dominant commensal organism in the human gut

This receptor agonist helps guide several metabolic pathways in the body