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The pathophysiology of RASopathies is centred on excessive foetal astrogliogenesis and prevalence of functionally deranged astrocytes

We further corroborated these conclusions exploiting another DXd-based ADC (Datopotamab-DXd) and found that DXd-based drugs promote Topoisomerase I downregulation and senescence

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The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology: Advances in Integrative Anatomy and Evolutionary Biology , 291 (6), 653-660