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In patients with haemochromatosis, and in other cases where medical treatment is not effective, then manage with venesection Long-term follow up is required as patients with poorly controlled PCT are more likely to get cirrhosis and liver carcinoma Variegate porphyria Patients are best managed by a department that specialises in porphyria Family members need screening Erythropoietic protoporphyria Refer patient to a specialist The most common treatment is oral beta-carotene The -melanocyte stimulating hormone Afamelanotide is the most effective treatment but is not currently available in the UK on the NHS Other resources Patient support group - The British Porphyria Association Disclaimer - the author PCDS cannot accept responsibility for any misleading or incorrect statements, and the management of individual patients remains the direct responsibility of the individual doctor