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A purified membrane protein from akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

[76] reported that targeted delivery of kartogenin (KGN) to synovial fluid MSCs (SF-MSCs) by engineered exosomes leads to even dispersion of KGN in the cytosol and strongly promotes the chondrogenesis of SF-MSCs in vitro and in vivo

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Anti-inflammatory action via adenosine accumulation and cytokine inhibition

doi: 10.21037/jss-25-4 Walley Alexander Y

In addition, the surface modification of islets to avoid direct contact with blood or immune cells might be another feasible strategy