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On the inflammatory front, curcumin inhibits microglial activation and downregulates the expression of inflammatory enzymes and cytokinesfor instance, it suppresses iNOS and COX-2 induction and lowers levels of TNF- and other interleukins in activated glial cells (72)

Most studies (17 of 27) had a low risk of bias, 36,38,41,43,44,45,46,47,48,50,53,54,55,58,59,60,61 7 had some concerns of bias, 37,40,42,51,56,57,62 and 3 studies were categorized as having a high risk of bias

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While allergic reactions to glutathione are rare, they can occur in some individuals, leading to symptoms such as skin reactions, respiratory issues, and gastrointestinal distress