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Ludwig van Beethoven (1770-1827) Date: October 27, 2011 Event: Music Department Noonday Concert Location: Dickinson College Michael Williamson Hoke Dalla Sua Pace

B4G2 induces mitochondrial apoptosis by the ROS-mediated opening of Ca(2+)-dependent permeability transition pores

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156 utilized ZIP6 residues 240253 (ZIP6-Y) and ZIP10 residues 4659 (ZIP10B) to target ZIP6 and ZIP10, preventing their heteromer formation and thereby impeding the progression of mitosis