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In letrozole-induced PCOS rats, administration of 600 mg/kg black cumin extract significantly decreased serum testosterone levels and restored estrous cyclicity

Specifically, cancer cells induce oxidative stress in neighboring CAFs, triggering autophagy and mitophagy, which in turn reinforce the CAFs to undergo metabolic reprogramming towards aerobic glycolysis

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doi: 10.1016/j.abb.2014.05.006

Inhibits melanin overproduction Glutathione shifts melanin production from dark pigment (eumelanin) toward lighter pigment (pheomelanin)

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