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In people living with HIV (PLWH), even under virological suppression, studies report a higher frequency of mtDNA mutations than in age-matched HIV-negative individuals ( mtDNA integrity is essential for supporting the high metabolic demands of immune cell proliferation and effector function ( Although not yet used in routine clinical practice, assessing mtDNA integrity remains valuable in research setting

Available from: [DOI] [PubMed] [Google Scholar] 381.Shah YM, Matsubara T, Ito S, Yim S-H, Gonzalez FJ

Targeting Mitochondrial-Derived Reactive Oxygen Species in T Cell-Mediated Autoimmune Diseases

*Correspondence: Liming Shen [email protected] This article was submitted to Autism, a section of the journal Frontiers in Psychiatry Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

S.SanyalR.MishraA.PandeyD

For critical applications, reconstitute only the volume needed for immediate use and prepare fresh batches every 57 days