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Antioxidants 8:426

Immunology 158 , 362374 (2019)

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10a) in 3D, it led to a disruption in the formation of tumor spheroids (Supplementary Fig

Eligible conditions included pulmonary infectionstypically defined as pneumonia caused by bacterial, viral, or other pathogenic agents and often associated with acute pulmonary function impairmentchronic obstructive pulmonary disease (COPD), characterized by progressive airflow limitation and chronic airway inflammation, and interstitial lung diseases (ILDs), which involve diffuse inflammation and fibrosis of the lung parenchyma, leading to restrictive ventilatory defects

It is intriguing that 4-HNE, as a signaling molecule, can regulate the expression of many transcription factors while enhancing the antioxidant mechanism of cells