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Anaphylactic shock and death have been reported with administration of parenteral vitamin B12 (see WARNINGS)

IM injections are delivered into a large muscle group, typically the thigh, gluteal muscle, or upper arm, and are absorbed over a period of minutes to hours

Most patients receive injections once weekly

Cardiovascular benefits: Clinical trials have demonstrated that tirzepatide can reduce the risk of major adverse cardiovascular events, such as heart attacks and strokes, in people with type 2 diabetes who have established cardiovascular disease

Here's something the internet won't tell you when it sells you research-grade powder: with an unregulated compound, what's in the bottle matters as much as the molecule itself

Fortin JL, Baud FJ, Astier A, Barriot P, Lecarpentier Y