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With long-term use, corticosteroids can result in many side effects, including a need for increased doses to manage physical stress, steroid withdrawal syndrome, insomnia, mood changes, elevated blood pressure or blood sugar levels, infections, gastrointestinal symptoms, increased appetite and subsequent weight gain, osteoporosis, cataracts or glaucoma in the eyes, hardening of the arteries or avascular necrosis

Upon entry into enterocytes, tocochromanols and other fat-soluble compounds may accumulate in lipid droplets

Among US adults in NHANES, the rate of low serum B12 was 3% at a cutoff of 200 pg/mL and 26% at a cutoff of 350 pg/mL

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These functional isoforms differ in their translation start site, resulting in length variations, with isoform A consisting of 222 amino acids and isoform X1 containing 264 amino acids, including an additional 42 amino acid segment at the N-terminus