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If the goal is to taper off retatrutide, the more common approach is to maintain the CJC/Ipa layer during and after the retatrutide taper to support recomposition

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Preclinical research has also looked at MGFs local signaling role separately from the IGF-1 receptor pathway, suggesting it may have effects specific to muscle micro-injury response rather than simply mimicking IGF-1 systemically

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