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When ingested as a nutritional supplement preferably in the racemic mixture form, LA contains two isomers (1:1 of R-LA and S-LA), in which S-LA may prevent polymerization of R-LA and thus increases the bioavailability of the later (De Araujo et al., LA is found in both vegetable and animal-based foods, identified as lipoyl-lysine (coupling of LA to specific lysine residues

Prothrombotic changes, such as erythrocytosis and enhanced platelet reactivity, further contribute to an increased risk of acute cardiovascular events, including myocardial infarction and sudden cardiac death

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When applied to areas such as the joint tendons, this could lead to not only the tendon healing but total regeneration over time and also reduction in joint pain and inflammation

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