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The BBB separates the blood and the brain interstitial fluid (ISF, also referred to extracellular fluid, ECF), and it is a key player in drug delivery to the brain (Fig

But undeniably, those results were influenced by numerous factors, including variations in study methodologies, sample size, exposure assessment accuracy, and pathogenic complexity

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These findings suggest Dihexa not only prevents synaptic loss but actively promotes synapse formation even in the presence of Alzheimer's pathology