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These metabolites also reprogram lipid metabolism by downregulating SREBP-1c and upregulating CPT-1-mediated fatty acid -oxidation, thereby reducing hepatic lipid deposition (Nanji et al., 2003)

Notably, because the cell metabolism also produces H 2 O 2 , the MSCs+H 2 O 2 +Ru-hydroxide can maintain a relatively stable concentration of ~0.38 M H 2 O 2 , which is below the 1 M threshold and comparable to the level in the bare MSCs group without any treatment

Systematic error removal using random forest for normalizing large-scale untargeted lipidomics data

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The reduced dihydrolipoate residue is then oxidized by FAD and the liberated electrons are passed to NAD yielding NADH