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showed that glycyrrhizin can prevent ferroptosis in cells and in an animal model of acute liver failure by regulating iron levels, the GSH/GPX4 pathway, and the NRF2/HO-1/HMGB1 pathway

Often the patient will be ingesting very high amounts of carbohydrates when first seen and weight gain often follows

Peptide pools more reliably broaden the cytotoxic T-cell repertoire and may improve outcomes within individual cohorts, but a clear survival advantage over single-peptide strategies has not been demonstrated in randomized melanoma trials (Table 1)