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Tobacco contains approximately 4,000 chemicals, of which nicotine, carbon monoxide and other components stimulate blood pressure, lead to coronary AS, increase blood and platelet viscosity, reduce the ability to dissolve blood clots and oxygen-carrying capacity of hemoglobin, and even induce ventricular fibrillation, increasing the incidence of cardiovascular events (46, 47)

GLP-2 receptor in POMC neurons suppresses feeding behavior and gastric motility

Therefore, additional protective mechanism via exogenous/dietary antioxidants may be required

An estimated 6% of people in the US aged 60 or older have a vitamin B12 deficiency, while about 20% have low to normal or borderline deficient levels

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