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This review aims to summarize the current knowledge regarding Se deficiency and excess in pregnancy outcome as well as to briefly describe the challenges and controversies concerning Se supplementation in pregnant women with Se deficiency with or without concomitant thyroid disease

There have been recent placebo-controlled pilot studies that have looked at NAC in ASD patients directed toward the treatment of irritability, aggression, self-injurious behavior and tantrums [26,27]

NAC, a precursor of L-cysteine, is a powerful antioxidant that acts as a scavenger of free radicals, particularly oxygen-derived radicals 141

Moreover, several studies reported how neuroinflammatory conditions may be present in ASD patients, which are commonly linked and supported by high levels of ROS