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It is also a shame given the risk calculations in my mind for these small, short chain peptides is far different than a traditional pharmaceutical drug, given this is, in some ways, replacing/replenishing an endogenous gastric peptide that appears to decrease with age/stress

Resources: Pickart, L., & Margolina, A

It has decades of randomized controlled trial data behind it and is widely regarded as the reference-standard topical retinoid against which newer molecules are measured

It plays a pivotal role in various biological processes, including wound healing, tissue regeneration, and skin health

Active Metabolites: Does first-pass metabolism generate active metabolites contributing to biological effects

10.1016/j.copbio.2014.12.024 Curr