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cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging

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10.1002/em.20474 59 JacksonM

Combinations of inhibitors with competitive and non-competitive behavior were evaluated for cytotoxicity against MCF-7 and MDA-MB-231 cells to establish if synergistic activity could be achieved, i.e., if reduced doses of two combined compounds could achieve a similar effect to an individual compound