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Specific Contraindications: These medications are strictly not recommended for anyone with a personal or family history of Medullary Thyroid Carcinoma or a condition called Multiple Endocrine Nieplasia syndrome type 2 (MEN 2)

12.2 Pharmacodynamics In the osteoporosis treatment trial, the effect of Reclast treatment on markers of bone resorption (serum beta-C-telopeptides [b-CTx]) and bone formation (bone specific alkaline phosphatase [BSAP], serum N-terminal propeptide of type I collagen [P1NP]) was evaluated in patients (subsets ranging from 517 to 1246 patients) at periodic intervals