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3) The mechanisms involved in the adaptive response against oxidative stress mediated by ROS-responsive transcription factors, involving up-regulation of GSH-synthesizing enzymes, GSH-detoxifying enzymes and the hepatocellular efflux pumps

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In addition to identifying new genes not previously implicated in biotic or abiotic stress tolerance, our results also confirmed the previous findings that showed the involvement of some of these genes in both biotic and abiotic stresses

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During cerebral ischaemia, reduced blood flow deprives neurons of essential oxygen and nutrients, triggering excitotoxicity, mitochondrial dysfunction, and excessive production of reactive oxygen and nitrogen species (RONS)