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2023 Mar 29;15(3):e36864

CA IXdeficient mice display hyperplasia of the stomach mucosa associated with loss of parietal cells, impaired basolateral pH regulation, perturbed barrier functions, and chronic inflammation [56, 57]

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Zero adverse events were reported no scarring, infection, or complications

Pharmacokinetic Optimization strategies Dosage form improvement Develop sustained-release preparations to reduce injection frequency and enhance patient compliance