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The rationale for this approach is based on observations that patients who have pyruvate kinase deficiency have higher-than-normal levels of 2,3-BPG, while hexokinase-deficient patients have below-normal levels

For vitamin D insufficiency (2129 ng/mL), the dosing is 8000 IU daily for 4 weeks followed by an identical maintenance regimen (221)

T.VantlerM.et al (2006)

10.1002/acn3.54 18 ChenJ.ZhangZ.CaiL

Although 6-phosphoglucono--lactone is hydrolytically unstable and can undergo spontaneous (nonenzymatic) ring-opening at a significant rate, this hydrolysis reaction is greatly accelerated in the cell by the enzyme 6-phosphogluconolactonase (EC 3.1.1.31)

Our Liposomal Glutathione is also excellent for morning use, as it can be taken directly or mixed into a glass of water or juice