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PMID: 16547589

The more ancient family, here called the -type TrxRs for the species it was first described from (Moore et al., 1964), is found in all eubacteria, archaea, fungi, most protists, and most plants and algae (Fig

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In most cases, the condition is self-limited and responds to supportive care and symptomatic relief including rest, elevation if a dependent extremity is affected, and use of compression stockings